I have been using this software for the past couple of months, and it has been extremely helpful in picking up subtle patterns. I suffer ongoing migraine headaches (5+ years of daily symptoms), and Optimism has been helpful in following the effects of changes in medication. I have also, due to my own ineptness, needed some tech support, and James has been prompt, helpful and patient. I could not ask for more from the software, being incredibly flexible to customize to my needs, or the developer, so eager to help. Incidently, this software could easily be adapted for depression sufferers, those with chronic pain, or even athletes. It is ideal for someone working with a doctor to adjust medication levels, and needing to determine the effectiveness of the changes, regardless of the medical condition being treated. Because the interface can be completely customized, and because it allows for not only yes/no but numerical values for responses, Optimism can be completely tailored to track the information you need in fairly precise detail. This allows for a much easier, objective assessment of how you are doing over a period of time, or how changes are affecting you.